You can try different "source". Game Capture and Display Capture at the two best. Game Capture is best if OBS Studio recognizes the game. Display Capture if it doesn't. I previously used Display Capture + game in Windowed Fullscreen when OBS didn't see a game. I'd try these settings at first, to keep things simple (maybe switch "Medium" to "Slow", then go Slower and VerySlow if you have CPU to spare and good FPS): http://i.imgur.com/PDN66Qi.jpg http://i.imgur.com/yIAjvi8.jpg http://i.imgur.com/U0BVA1G.jpg You can also try a bitrate between 10 000 to 12 000, as I believe this is what Youtube prefers for 1080@60.